迪恩（简森·阿克斯 Jensen Ackles 饰）和萨姆（贾德·帕达里克 Jared Padalecki 饰）是两兄弟，生在温切斯特家族的他们，血统里便带着与生俱来的责任——成为“猎人”，专门对付危害人类的恶魔与超自然力量。22年前，他们的母亲遭遇恶魔毒手，因此父亲约翰（杰弗里·迪恩·摩根 Jeffrey Dean Morgan 饰）多年来一面试图追杀恶魔，一面训导两兄弟成为优秀猎人。不过，相比哥哥迪恩对“捕猎”的热衷，弟弟萨姆显然更爱普通生活，他进了斯坦福大学，有了美丽女友，一心要与古怪家庭脱离关系。怎料一次捕猎活动中父亲失踪，迪恩只能召来弟弟协助，萨姆先是勉为其难，但随着调查深入，他发现命中注定的事根本无法凭他个人力量改变……This television drama is about the two Winchester brothers, Sam and Dean, who were raised by their father, John, to hunt and kill all things that go "bump in the night" after his wife, Mary, was murdered by an evil supernatural being when the boys were young. 22 years later the brothers set out on a journey, fighting evil along the way, to find their recently missing father who, when they finally meet up with, reveals he knows what killed their mother, a demon, and has found a way to track and kill it. Meanwhile, Sam starts to develop frightening abilities that include death visions, visions of people dying before it actually happens. These visions are somehow connected to the demon who murdered his mother and its mysterious plans that seem to be all about Sam. When their father dies striking a deal with the very same devil that had killed his wife, the brothers, now alone and without their mentor, are determined to finish the crusade their father started. But disturbing revelations about Sam's part in the demon's apocalyptic plans are presented when John's dying last words to Dean are revealed.
推荐专题