男孩托马斯（迪伦·欧布莱恩 Dylan O'Brien 饰）在电梯中醒来，奇怪的是他除了名字之外什么都记不得。当电梯打开，他来到了一个陌生的地方“林间空地”。这里四周被高大的石头墙包围着，墙内住着许多男孩，有纽特（托马斯·桑斯特 Thomas Sangster 饰）、查克（布雷克·库珀 Blake Cooper 饰）、米诺（李基弘 Ki Hong Lee 饰）等人，他们都被困在迷宫里，而墙外还有一群巨大的怪兽威胁着。一天，电梯为他们送来了一个女孩特雷莎（卡雅·斯考达里奥 Kaya Scodelario 饰），她是来这里的第一个女孩。此后，迷宫逐渐开始发生变化，一切都陷入了混乱中，托马斯和特雷莎决定一起走上破解迷宫之路，找出迷宫背后令人不寒而栗的秘密。 影片改编自詹姆斯·达什纳撰写的同名反乌托邦科幻小说三部曲的第一本。Awakening in an elevator, remembering nothing of his past, Thomas emerges into a world of about thirty teenage boys, all without past memories, who have learned to survive under their own set of rules in a completely enclosed environment, subsisting on their own agriculture and supplies. With a new boy arriving every thirty days, the group has been in "The Glade" for three years, trying to find a way to escape through the Maze that surrounds their living space (patrolled by cyborg monsters named 'Grievers'). They have begun to give up hope when a comatose girl arrives with a strange note, and their world begins to change with the boys dividing into two factions: those willing to risk their lives to escape and those wanting to hang onto what they've got and survive.
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